Lysosomes serve enzymes that metabolize excess sugars and lipids into substances which cells can utilize. As lysosomes do not function properly, these sugars and fats accumulate in the cell rather than being used or disposed of. Lysosomal storage diseases are rare but can cause death if left untreated. There are more than 50 types of lysosomal storage disease. The most common types in infants and children include:

• Gaucher
• Niemann-Pick
• Fabry
• Krabbe
• Pompe
• Mucopolysaccharidoses (MPS)