Volatile organic compounds (VOCs) are chemicals that are widely used in industrial processes and are important due to their risks to human health. VOCs, which pose potential safety and environmental problems, are generally emitted through the air from volatile compounds or products containing them. The presence of VOCs in the blood at levels above the exposure limit is extremely harmful to health. Due to its toxic effects, exposure assessment is required. Detection of volatile organic compounds in the blood sample is very important to determine the exposure level.