Polyunsaturated fatty acids (PUFA) have important physiological functions and are key regulators of cell membrane properties. Among the PUFAs, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) compounds are known to have beneficial effects such as lowering blood lipid levels, reducing immune problems, inhibiting thrombogenesis, improving cognitive functions, alleviating depression and limiting tumor growth. In addition, observational studies have shown that omega-3 PUFA intake can prevent the occurrence and progression of multiple cardiovascular diseases. Morever, although the importance of intake of omega-6 fatty acids at the levels necessary for body health is known, changes in food consumption habits can lead to increases in the intake of proinflammatory ω-6 fatty acids precursors. Measurements for clinical benefit; It contains the Omega-3 Index consisting of EPA + DHA, EPA / AA ratio, EPA quantitation and DHA quantitation. In addition, determining the ratio of ω-6 / ω-3 is of great importance. Because a high ω-6 / ω-3 ratio increases the pathogenesis of many chronic diseases such as cardiovascular disease, cancer, inflammatory and autoimmune disease, rheumatoid arthritis, asthma, while a low-6 / ω-3 ratio (high ω-3 level) has negative effects. can suppress.