HVA,VMA,5-HIAA KIT

HVA-VMA-5HIAA in Urine LC-MS/MS Analysis Kit

Laboratory measurement of vanillylmandelic acid (VMA), the product of epinephrine, norepinephrine metabolism, and homovanillic acid (HVA), a terminal metabolite of dopamine, and 5-Hydroxyindolacetic acid (5-HIAA) the end metabolite of serotonin is used to enhance clinical diagnosis and management of catecholamine-secreting neurochromaffin tumors such as neuroblastomas. Neuroblastoma usually emerges in children and accounts for 7–10% of childhood cancer; approximately 90% of these tumors produce catecholamines (CAs). Pheochromocytoma is a rare neuroendocrine tumor arising from the chromaffin cells of the adrenal medulla and characterized by producing excessive amounts of CAs and their metabolites.

  • Highlights

    Simultaneously quantification of HVA, VMA and 5-HIAA

    Dilute and shoot sample preparation procedure

    Total run time 10 min.
  • Parameters

    Homovanillic acid

    Vanillylmandelic acid

    5-Hydroxyindolacetic acid
  • Matrix

    Urine

Sample Preparation


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