THRAPEUTIC DRUG MONITORING KIT

THRAPEUTIC DRUG MONITORING KIT IN SERUM/PLASMA SAMPLES

Jasem LC-MS/MS method for therapeutic drug monitoring introduces a simple procedure for detecting and quantifying compounds such as drugs of abuse, antidepressants, antipsychotics, antiepileptics etc. in urine samples. According to customer needs, Jasem clinical toxicology kit is suitable to extend the drug list with new compounds.

  • Features

    • Quick and simple sample preparation steps
    • No need to use SPE for clean up
    • Protein precipitation process
    • Simultaneous analysis of different drug groups-total run time is 12 minutes
    • Method allows to extend the drug list
  • Matrix

    • Serum / Plasma

Sample Preparation For Serum/Plasma Samples


  • Step 1

    Pipet 100 µl of serum or plasma sample onto a clean centrifuge tube1

  • Step 2

    Add 900 µl of Reagent-1 into the tube and vortex for 15 seconds

  • Step 3

    Centrifuge the precipitated sample at 3000 rpm for 5 min

  • Step 4

    Transfer the supernatant into a HPLC vial

  • Example chromatogram of Jasem TDM Method

  • Content of Jasem 1 ppm clinical toxicology mixture

     

     

    1 6-Acetylmorphine

    31 Dilazem

    61 Meormin

    91 Phenytoin

    2 7-Aminoclonazepam

    32 Diphenhydramine

    62 (±)-Methadone

    92 Prilocaine

    3 Alprazolam

    33 Doxepin

    63 (±)-Methamphetamine 93 Propafenone

    4 Amisulpride

    34 Doxylamine

    64 Methylecgonine

    94 (±)-Propranolol

    5 Amitriptyline

    35 Escitalopram

    65 Metoclopramide

    95 Propyphenazone

    6 Amlodipine

    36 Etodolac

    66 Metoprolol

    96 Pseudoephedrine

    7 Amphetamine

    37 Famodine

    67 Metronidazole

    97 Queapine

    8 Atenolol

    38 Fentanyl

    68 Mianserin

    98 Ranidine

    9 Atropine

    39 Fluconazole

    69 Midazolam

    99 Risperidone

    10 Benzoylecgonine

    40 Flunitrazepam

    70 Mirtazapine

    100 Sertraline

    11 Biperiden

    41 Fluoxene

    71 Moclobemide

    101 (±)-Δ9-THC

    12 Bromazepam

    42 Flurazepam

    72 Morphine

    102 11-nor-9-Carboxy-Δ9-THC  (THC-COOH)

    13 Buprenorphine

    43 Flurbiprofen

    73 Naproxen

    103 (±)-11-Hydroxy-Δ9-THC (THC-OH)

    14 Carbamazepine

    44 Fluvoxamine

    74 Nifedipine

    104 (±)-Thiopental

    15 Chlordiazepoxide

    45 Gabapenn

    75 Nitrazepam

    105 Thioridazine

    16 Chlorpheniramine

    46 Glybenclamide

    76 Nordiazepam

    106 Tramadol

    17 Chlorpromazine

    47 Haloperidol

    77 Nortriptyline

    107 Trimipramine

    18 Citalopram

    48 Hydroxyzine

    78 Olanzapine

    108 Venlafaxine

    19 Clobazam (Urbadan)

    49 Imipramine

    79 Opipramol

    109 Cocaethylene

    20 Clomipramine

    50 Ketamine

    80 Ornidazole

    110 Norbuprenorphine

    21 Clonazepam

    51 Lansoprazole

    81 Oxazepam

    111 Dihydrocodeine

    22 Clozapine

    52 Leveracetam

    82 Oxcarbazepine

    112 Ethylmorphine

    23 Cocaine

    53 Lidocaine

    83 Pantoprazole

    113 Oxycodone

    24 Codeine

    54 Loperamide

    84 Acetaminophen

    114 EDDP perchlorate

    25 Desipramine

    55 Lorazepam

    85 Paroxene

    115 Ephedrine

    26 N-Desmethylclomipramine

    56 (±)-MDA

    86 Pentobarbital

    116 MBDB

    27 Dextromethorphan

    57 MDEA

    87 Pentoxifylline

    117 Paliperidone

    28 Diazepam

    58 (±)-MDMA

    88 Pethidine

    118 Desmethylolanzapine

    29 Diclofenac

    59 Medazepam

    89 Pheniramine

    119 Desmethylclozapine

    30 Digoxin

    60 Memanne

    90 Phenobarbital

     

ADAPTING DIAGNOSTICS IN CHROMATOGRAPHY COUPLED MASS SPECTROMETRY..

Products

Contact Us

The easiest way is to fill the contact form. Simply mail us to info@jasem.com.tr or give us a call +902165720200